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Federal MPJE Practice Questions

Federal MPJE Practice Questions

Prepare for the federal portion of the MPJE with a comprehensive set of practice questions based on current federal pharmacy...

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Last updated May 19, 2025

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MPJE Review Team TRAN

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Prepare for the federal portion of the MPJE with a comprehensive set of practice questions based on current federal pharmacy laws. This question bank includes over 6,000 high-yield, exam-style questions with detailed explanations. Ideal for reinforcing key concepts in DEA regulations, controlled substances, labeling, and more.

Question Bank Content

Section 1: DEA & Controlled Substance Law 9 Topics

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Topic 1: DEA Registration Requirements

Topic 2: Controlled Substance Schedules (I–V)

Topic 3: DEA Forms (222, 106, 41, 224, 225)

Topic 4: Ordering & Receiving Controlled Substances

Topic 5: Inventory Requirements (Initial, Biennial)

Topic 6: Recordkeeping & Storage Requirements

Topic 7: Reporting Loss or Theft (DEA 106, significant loss)

Topic 8: Disposal/Destruction (DEA 41, Reverse Distribution)

Topic 9: DEA Inspections and Administrative Warrants

Section 2: Prescriptions & Dispensing 9 Topics

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Topic 10: Valid Prescription Requirements

Topic 11: E-Prescribing of Controlled Substances (EPCS)

Topic 12: Emergency Oral C-II Prescriptions

Topic 13: Partial Fills (C-II and CIII–V Rules)

Topic 14: Transfers of Prescriptions

Topic 15: Refill Limits and Expirations

Topic 16: Faxing C-II Prescriptions (Hospice, LTCF, Parenteral)

Topic 17: Mailing Controlled Substances (USPS Regulations)

Topic 18: Dispensing Without Prescription (CV Exceptions)

Section 3: Pharmacy Operations & Responsibilities 8 Topics

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Topic 19: Pharmacist’s Corresponding Responsibility

Topic 20: Federal Labeling Requirements

Topic 21: OBRA ’90: Counseling, DUR, Patient Records

Topic 22: HIPAA Compliance in Pharmacy Practice

Topic 23: Drug Supply Chain Security Act (Track & Trace)

Topic 24: Ryan Haight Act (Online Pharmacies)

Topic 25: Combat Methamphetamine Epidemic Act (Sales Limits)

Topic 26: Overview of USP 795 / 797 / 800

Section 4: Compounding & Outsourcing 4 Topics

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Topic 27: 503A vs 503B Compounding Pharmacies

Topic 28: FDA Oversight in Compounding

Topic 29: Interstate Distribution & MOUs

Topic 30: Bulk Drug Substances (APIs) & Restrictions

Section 5: Federal Drug Laws & FDA Regulations 6 Topics

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Topic 31: Food, Drug, and Cosmetic Act (FDCA)

Topic 32: Durham-Humphrey Amendment (Rx vs OTC)

Topic 33: Kefauver-Harris Amendment (Efficacy & Safety)

Topic 34: Prescription Drug Marketing Act (PDMA)

Topic 35: Orange Book & Therapeutic Equivalence

Topic 36: REMS Programs and MedGuides

Section 6: Institutional & LTCF Pharmacy Rules 5 Topics

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Topic 37: Hospital Medication Orders vs Prescriptions

Topic 38: Emergency Kits (Hospice, LTC)

Topic 39: DEA Rules for LTC, Hospice, and ADS

Topic 40: Chart Orders vs Traditional Prescriptions

Topic 41: Barcoding and EHR Regulations

Section 7: Special Drug Handling & Investigational Use 4 Topics

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Topic 42: Investigational Drug Requirements

Topic 43: Drug Samples (Restrictions & PDMA Rules)

Topic 44: Drug Recall Classes (I, II, III)

Topic 45: Special Population Medications (Methadone, Buprenorphine, Clozapine)

MPJE Review Team TRAN Instructor